Manufacturer: Dragon Pharma, Europe
Pharmaceutical name: Nandrolone Phenylpropionate
Pack: 10 ml vial (150 mg/ml)
Active Life: 4 - 5 days
Average Dose: 25 - 100 mg/week
Water Retention: Yes, but less than testosterone
Liver Toxic: No
NPP 150 by Dragon Pharma
NPP 150 is an injectable steroid, this drug contains Nandrolone Phenylpropionate and is made by Dragon Pharma, Europe.
NPP 150 is chemically related to the male hormone. Compared to testosterone, it has an enhanced anabolic and a reduced androgenic activity. This has been demonstrated in animal bioassays and explained by receptor binding studies. The low androgenicity of nandrolone is confirmed in clinical use. In the human, NPP 150 has been shown to positively influence calcium metabolism and to increase bone mass in osteoporosis. In women with disseminated mammary carcinoma, NPP 150 has been reported to produce objective regressions for many months. Furthermore, Nandrolone has a nitrogen-saving action. This effect on protein metabolism has been established by metabolic studies and is utilised therapeutically in conditions where a protein deficiency exists such as during chronic debilitating diseases and after major surgery and severe trauma. In these conditions, Nandrolone Phenylpropionate serves as a supportive adjunct to specific therapies and dietary measures as well as parenteral nutrition, due to it's faster acting nature Nandrolone Phenylpropionate is preffered in situations where a faster clinical response is required over it's chemical variant Nandrolone decaonate.
It’s a progestin, like any Nandrolone derivative, and is made by removing the carbon atom at the 19th position of the Steran Nucleus of testosterone. However, although it’s a progestin, Nandrolone (regardless of ester) doesn’t produce much of what we could properly call estrogenic side effects. Any side effects from Nandrolone Phenylpropionate would therefore more properly be termed progestenic in nature- as it only converts to estrogen at roughly 20% the rate of testosterone.
Regardless of ester, and water retention not withstanding, we find that all of the characteristics of found in one type of Nandrolone are found in any other. Nandrolone, probably owing to its progestenic nature has the ability to improve collagen synthesis as well as bone mineral content. Clearly this would be a huge benefit to athletes with connective tissue problems or other joint issues, although drug-tested athletes need to avoid NPP 150 because of their detectability in urine for a year to eighteen months after administration. Also, since it is progestin (with slight estrogenic ability), it probably has some very beneficial effects on the immune mediated anti-inflammatory process, thereby soothing joints as well as helping to heal them.
NPP 150 HOW DOES IT WORKS?
NPP 150, and nandrolone in general, has a number of benefits for athletes, it increases levels of serotonergic amines in the brain, these chemicals contribute to aggressive behavior, this could help athletes to train harder and improve speed and power. NPP 150 also increases levels of IGF-1 in muscle tissues. This may be another way that makes nandrolone highly anabolic. NPP 150 also benefits the athlete by increasing the number of androgen receptors (AR) one study showed that NPP 150 given to rats at a dosage of 6 mg/kg of bodyweight combined with muscle functional overload (muscle functional overload gives a similar effect to resistance training) had a 1,300% increase in AR protein concentrations. There is a direct link to muscle growth and AR levels. NPP 150 also seems to be a promising fat loss agent, men given the drug had reduced levels of subcutaneous (under skin) adipose (fat) tissue, visceral (gut) fat loss was not as good however. The fat loss effect seems though to be dose dependant, in one study NPP 150 at a daily dose of 1, 4, or 10 mg per kg of bodyweight the 10 mg dose had the greatest effect on fatloss, thus displaying a dose respondant curve with NPP 150. The more you use, the more results you?ll get, with regards to this drug.
NPP 150 is used to treat anemia by stimulating red blood cell production, and an increase in RBC count can improve endurance during exercise via better lactic acid clearing and oxygen delivery. The blood is also better enabled to carry nutrients to muscle tissue to aid in repair, administration also increases the rate of muscle glycogen repletion after exercise helping the athlete dramatically improve recovery after strenuous physical exercise. Athletes who require a high level of endurance in their chosen sport can benefit from the use of NPP 150. A favorite with bodybuilders who suffer with sore joints, NPP 150 can also improve collagen synthesis, which may improve joint function and alleviate joint pains.
NPP 150 can be highly useful in either "bulking" or "cutting" cycles, and it would seem that diet and dosages are the determining factors of whether a cycle with this drug will be one or the other. Due to its highly anabolic nature coupled with low androgenic properties it can be incorporated into a mass cycle, usually stacked with testosterone and a powerful oral like possibly Oxymetholone (Anadrol) or Methandrostenolone (Dianabol). NPP 150 can thus be part of a classic bulking cycle. For a cutting cycle NPP 150 is usually be combined with other short-estered injectable anabolic steroids and one of the DHT derived orals such as Stanozolol (winstrol) or oxandrolone (Anavar). NPP 150 is said to produce good mass and strength gains in both cutting and bulking cycle phases. When one is planning a cutting cycle one must take caution if combining the 19-nor-testosterone derivative trenbolone with nandrolone. Trenbolone Acetate, although a powerful drug for lean muscle gains, strength, and fat loss is also a strong progestin with a binding affinity to the PgR of 60% (3x that of nandrolone). The elevated prolactin, can worsen HPTA insult, often causing the user to spend more money on preventative measures, the combo may also result in a difficult PCT protocol to regain natural testosterone production.
NPP 150 SIDE EFFECTS:
Although many nandrolone lovers claim that it is one of the safest anabolic steroids, if not the safest. It does have side effects that can be bothersome in hypersensitive individuals, such as acne, excitation, insomnia, nausea, diarrhea and bladder irritability. More serious side effects include testicular atrophy, impotence and gynecomastia. NPP 150 use has been shown to be safe and easy on the lipid profile, often improving HDL Cholesterol Impotence can be offset by stacking the nandrolone with a higher testosterone. NPP 150 also causes the "shut down" of natural testosterone production. Thus an exogenous source must be provided, the increased prolactin levels from the use of a progestinic steroid contribute to HPTA shut down and testicular atrophy which can be treated with a combination HCG and Bromocriptine. Besides using Bromcriptine to lower prolactin levels, the anti-estrogens fulvestrant or Letrozole on be taken to down regulate the progesterone and estrogen receptor.
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