Pharmaceutical name: Dutasteride
Pack: 30 caps (0.5 mg/cap)
Avodart by GlaxoSmithKline
Avodart - mens health drug, this drug contains Dutasteride and is made by GlaxoSmithKline.
Dutasteride is a reductase inhibitor initially developed and approved for medical use in the treatment of benign prostatic hyperplasia. This is accomplished via the inhibition of 5-alpha-reductase. 5-alpha-reductase is an enzyme, which when it interacts with testosterone , produces dihydrotestosterone (DHT). Therefore Dutasteride helps in blocking the formation of DHT in users. This is important since 5-alpha-reductase is found in high concentrations in such areas of the body as the prostate and scalp. By inhibiting these interactions in these tissues Dutasteride can help to reduce the levels of androgenic activity and prevent some conditions from occurring or reduce their severity.
In terms of the use of Avodart for steroid users it would be related to the easing of several androgenic side effects often associated with the use of some anabolic and androgenic steroids. Of course due to the originally intended medical purpose of the drug, steroid users suffering from prostate conditions due to their anabolic steroid use could be well served to use a drug such as Dutasteide. This will likely ease some of the discomfort caused by the activity of the DHT in the prostate tissue and related conditions. Similarly the androgenic activity of DHT in the scalp leading to hair loss can also prevented in some males with the use of a reductase inhibitor like Dutasteride. If the hair loss experienced by the user is related to an increase in the concentration and/or level of DHT in the tissue the administration of dutasteride can help to reduce or prevent the severity of this side effect. A third side effect that the drug may help with is oily skin and/or acne. This androgenic side effect may be prevented or at the very least reduced in severity with the ministration of Avodart. However, anecdotally the results of this have been mixed to say the least and relatively few users administer the drug for this purpose.
Avodart HOW DOES IT WORKS?
For the maximum suppression of DHT levels that Avodart can accomplish it appears that a dose of approximately 5 milligrams per day is required. After two weeks of this dosing it has been shown that a ninety percent reduction in DHT levels in the body can be achieved. However many users will not require a dose that large to achieve the results that they are looking for, namely the prevention of androgenic side effects. Many users will use smaller doses in the range of 25mgs every day or 5mgs every other day. However due to the active life of the compound, twenty-four to forty-eight hours, every other day dosing is as infrequently as one should administer the drug. As always users should begin using the drug at the smallest dose that delivers the results that they are looking for to ensure that the severity of the side effects of the drug are minimized.
When discontinuing the use of Dutasteride there appears no need for a tapering of the drug to prevent a major rebound in DHT levels of the user. While obviously these levels will return to their normal concentrations no dramatic rise should be seen by the user. As well, at this time there appears no maximum duration that users should limit themselves to when using Avodart. As will be described below, there are no long term side effects associated with the continuous use of this drug other then temporary sterility, however as will be explained below this condition appears to be only temporary and should not be a major concern for most users.
Take Avodart by mouth once daily, with or without food. Swallow the medication whole. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. It may take 3 to 6 months before you notice an improvement of your symptoms.
Store Avodart at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets. Avodart capsules may soften and leak if stored at high temperatures. If your capsules crack and leak, do not use them. If your skin comes in contact with the leaking capsules, wash the area immediately with soap and water.
Avodart SIDE EFFECTS:
In terms of side effects related to the use of Avodart, it appears that all are related to its action as a reductase inhibitor and the lack of dihydrotestosterone (DHT) circulating in the system of the user when using this drug. There are no toxicity issues related to the use of Avodart and there have been seemingly no serious related side effects to the long term use of the drug in males.
Despite the lack of long term side effects for users there is one significant side effect that may affect some males. This is namely temporary sterility. This effect does appear to be only temporary with no long term damage to the ability of the user to produce healthy sperm capable of procreation once administration of the drug ceases. However users hoping to bear children will likely have to discontinue their use of the drug to enhance their chances of success. Dutasteride is so successful at causing temporary sterility in males that it has been studied as part of a combination of drugs that could be used as male birth control. However these studies remain in their preliminary stages. In any case, many steroid users will already be experiencing temporary sterility due to their use of anabolic steroids so this will not be an additional burden for the vast majority of users.
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